Platform · Predict

Fold a sequence. Right now.

Paste a single-chain amino-acid sequence and we'll fold it via ESMFold (Meta's public API), render the structure in Mol*, and report mean pLDDT, length, and confidence band. Up to ~400 residues per call. Sequences you submit are transmitted to Meta’s public ESMFold service for folding; do not paste confidential, proprietary, or regulated data.

Sequence (single chain · AA, no whitespace)

Model

Mol* viewer · live result Idle

No structure loaded. Paste a sequence and press Predict. Folding takes 5–30 seconds.

Model confidence · pLDDT Very high ≥90 Confident 70–90 Low 50–70 Very low <50

Mean pLDDT

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Length (aa)

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Confidence band

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Fold time

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Improvement loop

Mutate. Re-fold. Compare.

One residue at a time. Start with the sequence above, substitute a position, and we'll re-fold via ESMFold and report the pLDDT delta. The full improvement loop — module substitution, quantum refinement, and wet-lab retrain — runs inside the platform for active customers.

Mutation round

Pick a position and a new residue. We mutate the baseline sequence and re-fold. BLOSUM62-conservative swaps recommended for sanity.

Position (1-indexed)

New residue

Result

Comparison vs the baseline. Mutant structure replaces the viewer above.

Baseline pLDDT

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Mutant pLDDT

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[ready]

Pick a position, choose a residue, run. Output appears here.

Evidence verification

Anyone can verify. No login required.

Every result NOVA-3 produces is anchored as an Evidence Bundle — SHA-256 root committed to Bitcoin via OpenTimestamps. Paste any bundle ID to see its recorded anchor, then verify it yourself, independently, with ots verify <bundle>.ots against the public chain — you never have to take our word for it.

Try it · verify any bundle

Public verification widget

POST /v1/evidence/{id}/verify

Verification result appears here. Calls /v1/evidence/{id}/verify against the backend.